一 | (ECNS) -- China's pharmaceutical industry accelerated innovation in the first half of this year, with domestic companies steadily improving their R&D capabilities and growth momentum continuing to strengthen, data showed. China's first broad-spectrum targeted anticancer drug entered clinical use at major hospitals across the country this year. It took only eight months to go from submission to market approval. A total of 38 innovative drugs were approved for marketing in China in the first half, of which 31 were developed domestically, more than 80% of the total. Eleven drugs featuring new targets or new mechanisms were all developed independently by domestic companies, producing a number of world-first innovations. By the end of 2025, China had 4,751 innovative drugs under development, one-third of the global total and the largest pipeline of any country. Behind this concentration of results lies a steadily strengthening industrial base. China has a complete pharmaceutical supply chain. It is not only the world's largest producer of active pharmaceutical ingredients but has also built a production system covering every pharmaceutical category. This year, digital, intelligent, and green technologies have driven the industry's transformation and upgrading. At a biopharmaceutical company in Shanxi Province, a newly built AI-powered bio-computing center can identify the structures of millions of protein functional domains in a short time, screening out ineffective molecules directly. To date, China has supported 21 pharmaceutical firms in building excellent-level smart factories and has cultivated more than 300 green factories. In the first half, the added value of pharmaceutical enterprises above the designated scale grew 6.4% year on year, and exports held strong. The world's first chemotherapy-sparing drug for gastric cancer, launched this year, had already earned overseas revenue through licensing deals before it reached the market, and is now exported to multiple countries and regions. In the first half, the total value of China's innovative drug out-licensing deals reached $110 billion, the industry's export delivery value grew 9% year on year, and high-value-added products made up nearly 20% of the total. (By Tang Yuxian) 
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二 | KATHMANDU, Nepal -- A 5.2 magnitude earthquake and some aftershocks damaged nearly two dozen houses in the hilly Dhading district near Nepal's capital Sunday, an official said.The shaking also caused a landslide in the region, Hum Nath Parajuli, a district government administrator, said. Details were not immediately available.The area is nearly 60 kilometers (40 miles) west of Kathmandu, and the earthquake was felt in the Nepalese capital.Nepal’s National Earthquake Monitoring and Research Center gave a preliminary magnitude of 6.1. The U.S. Geological Survey provided measurements of a 5.2 magnitude with a depth of 24.7 kilometers (15.4 miles) and an epicenter near Bharatpur.Three tremors of 4.3, 4.1 and 3.8 magnitude also hit the region later Sunday, according to India’s Center for Seismology.The Press Trust of India news agency said the tremors were also felt in Bagmati and Gandaki provinces and caused panic among people. One woman suffered injuries in the Gorkha district, which adjoins Dhading, when she jumped from a two-story building, Parajuli said. Earthquakes are common in mountainous Nepal. A 7.8 magnitude earthquake in 2015 killed some 9,000 people and damaged about 1 million structures.。
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