昨夜星辰

《堡垒之夜》推出星球大战联动皮肤，需前往迪士尼乐园方可解锁_我的网站

A |     堡垒之夜 现已推出一款全新的《星际大战》专属皮肤，仅限造访两家迪士尼乐园的游客获取。

B | 这款名为“弃誓兵”（Forsworn Trooper）的皮肤是为造访加州阿纳海姆迪士尼乐园或佛罗里达州奥兰多迪士尼好莱坞影城的“千年隼号：走私者逃亡”体验项目的游客提供的专属游戏内奖励。    

    Qingyangshen, or Root of Auricledleaf Swallowwort, a traditional ethnic medicinal plant long used in Southwest China's Yunnan Province. Photo: Scrrenshot from website
A Chinese research team has identified a new potential target to develop antidepressant drug from Qingyangshen, or Root of Auricledleaf Swallowwort, a traditional ethnic medicinal plant long used in Southwest China's Yunnan Province, according to Kunming University of Science and Technology, Science and Technology Daily reported Sunday.
The team, led by professors Xu Tianrui and Xiang Cheng from the university's School of Life Science and Technology, found that Qingyangshen glycosides, the plant's core active compound, can alleviate depression-related behaviors by simultaneously suppressing inflammation, reducing oxidative damage and stabilizing neurotransmitters in the brain.
The findings were published in the international journal Phytomedicine.  
Depression has become a widespread mental health disorder globally, while existing clinical drugs fail to provide effective treatment for more than 30 percent of patients, according to the researchers. Previous studies have established a strong link between chronic inflammation and depression, but existing anti-inflammatory drugs have limited targeting capabilities, underscoring the need for new therapeutic targets and lead compounds.
Qingyangshen, a plant of the Cynanchum genus in the Apocynaceae family, has long been used as a traditional medicine by ethnic groups including the Naxi, Yi and Bai peoples in Yunnan, mainly for treating neurological conditions such as epilepsy and neurasthenia. 
The researchers systematically examined the pharmacological effects of Qingyangshen extract and its core active compound, Qingyangshen glycosides. Tests using mouse, zebrafish and fruit fly models repeatedly showed that the compound significantly improved depression-related behaviors induced by inflammation, according to the report.
To identify the compound's target, the team developed a dual-discrimination model for four subtypes of prostaglandin E2 receptors and combined it with AI-powered machine learning. The researchers screened hundreds of G protein-coupled receptors and identified the prostaglandin E2 subtype 4 receptor as the direct target of Qingyangshen glycosides.
Multiple molecular experiments confirmed that the compound binds directly to the receptor and acts as an inhibitory ligand. Further experiments involving animals with the receptor knocked out in the hippocampus showed that the antidepressant effects of Qingyangshen glycosides disappeared completely when the receptor was absent, providing the first in-vivo evidence that the receptor is essential for the compound's therapeutic effects.
    An illustration of the research. Photo: Screenshot from the website
The study establishes the prostaglandin E2 subtype 4 receptor as a potential new target for antidepressant drug development and points to a new approach to treating depression through inflammatory pathways. It also identifies Qingyangshen glycosides as a potential lead compound for developing highly targeted anti-inflammatory antidepressants, creating a research chain from ethnic medicinal plants and active compounds to drug targets and new drug development.
Global Times
。如果你近期打算前往这两个地点，那么你走运了！得益于迪士尼与 Epic Games 日益紧密的合作关系（以及你的 Epic 账户与迪士尼体验数据的关联），这款皮肤将属于你。如果你近期不打算前往这些地方……好吧，你可能有点尴尬。不过，如果能让你心里好受点的话，“弃誓兵”皮肤本身其实只是个不错的小赠品。它的设计相对简单，看起来像是用冲锋队盔甲残骸拼凑而成的，配有斗篷兜帽和护目镜。（兜帽下面是琼斯吗？）尽管如此，对于《星际大战》粉丝或 堡垒之夜 皮肤全收集玩家来说，Epic Games 此举无疑是发出了挑战，去争夺这款可能成为史上最稀有皮肤之一的作品。

C | （虽然可能没有鲁艾稀有？）对于近期无法前往迪士尼乐园的玩家，堡垒之夜 提供了一个全新的《星际大战》冒险项目，可以在家中的沙发上独自或与好友一起游玩。Star Wars: Smuggler’s Gambit 扩展了迪士尼乐园中的“走私者逃亡”体验，在乐园中，游客/玩家被分为飞行员、炮手和工程师，共同驾驶千年隼号。这似乎是一种巧妙的方式，既能将你的主题公园体验延伸到迪士尼围墙之外的家中，反之亦然。本杜（Hondo）是一个非常适合作为核心的角色，迪士尼可以做更多工作来扩展其主题公园游乐设施的故事，无论是《星际大战》还是其他内容。堡垒之夜 对举办《星际大战》联动活动并不陌生，Epic Games 的这款战术竞技游戏经常与那个遥远的星系进行跨界联动，以宣传《天行者崛起》、《曼达洛人》与古古，以及各种 Disney+ 的上线活动。

D | 今年晚些时候，备受期待的 堡垒之夜 迪士尼模式预计将上线，此前米老鼠之家在 2024 年对该游戏进行了 15 亿美元的投资。虽然细节仍处于保密状态，但有报道称该模式将包含类似于 ARC Raiders 的撤离类射击玩法。

Current article:http://www.chenzhuaigecoupuhongyuntuizei.sbs/news/20260826_8610410.htm

Published on:06:58:50